منابع مشابه
Integrative radiation systems biology
Maximisation of the ratio of normal tissue preservation and tumour cell reduction is the main concept of radiotherapy alone or combined with chemo-, immuno- or biologically targeted therapy. The foremost parameter influencing this ratio is radiation sensitivity and its modulation towards a more efficient killing of tumour cells and a better preservation of normal tissue at the same time is the ...
متن کاملIntegrative biology and systems biology
Demarcations of scientific fields have always followed either a conceptual breakthrough or have been a result of profoundly enabling technologies. Quantum theory and quantum mechanics revolutionized physics and engineering, but highenergy physics is a discipline fundamentally enabled by the linear accelerator. Similarly, the discovery of the structure of DNA gave birth to molecular biology; str...
متن کاملSystems Biology, Integrative Biology, Predictive Biology
The pursuit of science is based on empiricism enabled by advancing technologies. Theories then emerge that unify our understanding of natural order. The trinity of experimentation, theory, and technology that underlies the scientific method cannot be placed into a hierarchy of importance. Theoretical fields quickly lose substance in the absence of robust experimentation, and theoretical conundr...
متن کاملRadiation - perturbed signalling and systems radiation biology
In deep space astronauts are usually exposed to doses of ~ 1 mSv/day of charged particles, including HZE. Due to the exposure to GCR (e.g. during a mission to Mars), each cell nucleus of an astronaut would be traversed by a proton or by a secondary electron every few days, but only by an HZE ion every few months [1]. For this reason, besides the clustered properties of the incoming radiation on...
متن کاملIntegrative Systems Biology Visualization with MAYDAY
Visualization is pivotal for gaining insight in systems biology data. As the size and complexity of datasets and supplemental information increases, an efficient, integrated framework for general and specialized views is necessary. MAYDAY is an application for analysis and visualization of general 'omics' data. It follows a trifold approach for data visualization, consisting of flexible data pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiation Oncology
سال: 2014
ISSN: 1748-717X
DOI: 10.1186/1748-717x-9-21